Tag Archives: coronavirus

Big Pharma and COVID-19

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Big Pharma has a bad rep. And there are certainly valid reasons for that. Recent accounts of price gouging, particularly on common, life-saving drugs like insulin, have had consumers fuming. The cost of newer drugs is sky-high. And there have been an awful lot of drugs that were apparently sent to market too early, leading to a lot of dire side effects and drug recalls. Add to that the dubious practice of advertising prescription medications direct-to-consumer, and Big Pharma has abused the trust of the American people. The drugs they develop and sell may be – indeed, often are – beneficial and even life-saving, but that doesn’t seem to dissipate much of the cloud of bad feeling surrounding American pharmaceutical manufacturing.

Unfortunately, Big Pharma is likely going to be needed to help get us through the coronavirus crisis.

Sure, there are government agencies involved in the process of developing treatments and vaccines as well – the CDC, FDA, and NIH, to name a few. But even these institutes and organizations have been tainted by the dubious reputation of large drug companies. They are seen as in cahoots together, developing and testing drugs together, rushing them onto shelves and into doctors’ offices and hospitals, patenting the results, and pocketing the proceeds. Never mind whether that’s an accurate portrayal or not. That’s the public sentiment.

But where, exactly, do people believe that COVID-19 treatments and vaccines are going to come from, if not from Big Pharma and the various institutes? This is a novel virus, not likely to be much affected by drugs that already exist, though those should certainly be tried. Cures for other diseases have already been tested on COVID-19 and found wanting. Crackpot theories such as drinking bleach have made the rounds, with the potential to do great harm rather than help. Developing pharmaceuticals requires a huge investment of time and especially money. Big Pharma has to be big to work even as well as it does. So, yes, we should be looking to Big Pharma, if not directly for discovering a vaccine, at the very least for manufacturing and distributing it. Basically, there aren’t any mom-and-pop vaccine shops, biotech start-ups and upstarts notwithstanding. 

The question then becomes, if and when Big Pharma does develop drugs and vaccines for COVID-19 (far from guaranteed – we still don’t have a vaccine for HIV/AIDS), will people be willing to use them?

Scientific literacy is pretty low in the US right now. People don’t understand how vaccines work. Of course, that isn’t entirely the fault of the US education system. For decades now, there has been a growing party of anti-vaxxers that don’t just not understand the science, but refuse to even consider it. And facts don’t matter to those whose minds are made up. Still, after all these years and the complete discrediting of the guy who faked the study, people believe that vital childhood vaccinations cause autism.

Then there are the conspiracy theorists. I don’t know how many people there are who actually believe that Bill Gates is a Bond-style supervillain living on a volcano island, petting a long-haired white cat, but there certainly is a vocal subset of people who proclaim that, even should a vaccine for COVID-19 be produced, they will not use it, for fear of being microchipped, or submitting to the New World Order, or the Number of the Beast, or something. There may not be many people that far out on the limb, but their fervent influence has the potential to disrupt the herd immunity that ought to develop after the proper use of a new, effective vaccine.

So, the question becomes, if and when a treatment or vaccine becomes available, will people be smart enough to avail themselves of it? Or will the lack of trust in Big Pharma, the medical establishment, and medical science itself mean that sufferers will deny themselves treatment and go right on spreading the deadly disease?

I suppose it in part depends on how horrendous the death toll has been by the time that a vaccine exists, and how many family members, friends, and loved ones of doubters have died. 

 

 

 

Sick of the Virus

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I am sick of all the coronavirus blog posts and memes. But there are a few that I’m particularly sick of, especially the defiant ones and the conspiracy theories. Here’s what I think, for what it’s worth.

No, COVID-19 was not engineered by the Chinese or anyone else. There are plenty of viruses running around out in the wild and jumping species without anyone having to create them in a lab. Just because this one might affect you doesn’t mean it’s special.

No, wearing a mask does not violate your civil liberties. Miners and construction workers have to wear hardhats. Painters have to wear masks or respirators. Surgeons have to wear gowns, gloves, and masks. There are laws about these things designed to protect the people involved. If they can suck it up and wear protective equipment without protesting, so can you.

No, your need for a haircut does not trump my need for staying off a respirator.

Yes, social distancing is inconvenient, but it still beats having your lungs filled with fluid.

Yes, the employees in businesses that are still open probably hate wearing masks too and sanitizing their hands multiple times a day. But they don’t want to take your viruses back home to the people they care about.

No, it’s not necessary to carry guns to rallies protesting COVID-19 restrictions. Shooting legislators and health authorities will not make a bit of difference to the virus. Show some dignity, people. 

Yes, states have the right to respond to the virus in any way they choose, but they ought to consider that the virus does not care about state lines or crossing them. An informed national policy would make the crisis less of a crisis, though.

No, people in the 70s did not like gas rationing, any more than people during World War II liked rationing of gas, sugar, flour, shoes, and many other commodities. But they put up with it for the sake of a greater goal. In this case, the greater goal that restrictions are required for is preserving the lives of innocent people.

No, you don’t need that much toilet paper. The virus attacks the respiratory system, not the GI tract. Leave some for others, for goodness sake. Let’s not be ridiculous here.

No, Bill Gates, Hillary Clinton, and George Soros had nothing to do with the origin or spread of the virus and are not using it as an excuse to microchip everyone. (Microchipping your pets is still a good idea.)

Yes, staying at home and sheltering in place can be boring. And trying to work from home or home-schooling your kids can be frustrating. But there are people who do these things by choice, every day of the year, and if they can put up with it, so can you. Boredom and inconvenience are not sufficient reasons to risk death for yourself or others.

No, politics has no effect on the virus. It hits red states and blue states equally, all things being equal. Some states are just more on the ball than others when it comes to limiting the spread of the virus. Look at Ohio – a red state with a governor who listens to a doctor and takes her advice about proper precautions. The virus wasn’t “timed” to interfere with elections either. There’s no way you can make a virus do that.

Yes, you are acting like an idiot if you harass (or shoot) employees who insist you wear a mask. They are carrying out their employers’ instructions or the health regulations of their state, county, city, or other authority. They’re not to blame for it.

No, no one is whipping up fear for fear’s sake. COVID-19 is already fearsome enough without it. This is not a plot to use fear to control us all. 

Yes, I have an axe to grind, “skin in the game,” as it were. I am a senior with an immune condition and an immunosuppressant medication. My husband has diabetes and a job in the high-risk environment of a grocery store. If either one of us gets the virus, we’re likely both toast.

There. I hope I’ve made it clear. These “news” stories, rumors, memes, and speculation have to stop. There are people’s lives at stake here, folks.

Let’s Talk Viruses

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denisismagilov – stock.adobe.com

What’s up with viruses? What the hell are they, anyway? And how do those sly whatsits operate? Here’s a layperson’s guide.

Disclaimer first: I’m not a doctor, nor do I play one on TV. I’m not a microbiologist and I don’t think anyone plays one on TV. I’m simply a person who stayed awake in science class and has read a lot ever since.

First, let’s make this clear: Viruses have no brains. We can talk about a virus’s goals or intentions or strategies, but we’re at least partly anthropomorphizing or speaking metaphorically. A virus is a strand of DNA or RNA (in the case of COVID-19) wrapped in a shell which can glom onto bodily tissues so the virus can duplicate itself and move on to another host.

That’s what it does, and that’s about all it does. All a virus wants is to replicate itself and continue to do so. The fact that it makes you sick is quite incidental to that.

The incubation period – the length of time before you show symptoms of an illness – is important. It gives the virus time to multiply unnoticed within the body and infect others via bodily fluids before someone notices and tries to kill it off. The longer the incubation period, the more successful the virus is. Think HIV. It has an incubation period of years, which was what allowed it to be so successful at infecting a large number of people before anyone noticed.

The incubation period for coronavirus is, we think, about two weeks, give or take. You could have the virus without any symptoms during that time and all the while be spreading it by coughing, poor hygiene, or being too close to people. The masks that you wear may seem like they are protecting you, but actually they are preventing you from making other people sick.

Viruses are tricky bastards. They can – and do – evolve and mutate and jump species. That’s when a virus becomes particularly dangerous. If it mutates, as the flu virus does pretty much every year, no one has a natural immunity to it and unless a vaccine is created for that specific version, a lot of people get the flu.

Jumping species is another thing altogether. A virus can be living happily in a pig or a chicken or a bat or a monkey, not causing too much damage (at least not right away). But when a virus mutates so that it can infect and cause illness in another sort of animal (for our purposes, a human being), that’s when things get really tricky. The virus now has a population to infect that never encountered it before. It can burn through that population like wildfire. If the incubation period is short, the virus may burn itself out rapidly and not claim too many victims, as they die before having a chance to pass it on. But if the incubation period is longer, the virus gets a free ride to any number of new hosts.

And yes, people can get infected by eating the host animal. It’s not very likely, since most people eat their meat cooked, not raw. Bodily fluids and bites or scratches are much more dangerous, as is contamination with feces. But that’s not the only way that viruses are transmitted via animals. You know how viruses are passed from person to person without us having to eat each other’s flesh? Well, the virus can travel in the bodily fluids of other animals as well. So if you don’t wash your hands after feeding your chickens, or you stir up and breathe in some bat guano while you’re exploring a cave, or a mouse pees in your storeroom, any viruses lurking there can infect the unwary, if that virus is ready to jump species.

So, that’s a basic guide to viruses. And let’s be real about this. Viruses are all around us and spread quite naturally. There’s no real need to worry about a virus being manufactured and escaping from a lab. And need I say that Hillary Clinton, the deep state, Chinese supervillains, and George Soros have nothing to do with it? Yes, I suppose I do.